Table 1 Number of significant synovial lipids belonging to each lipid subclass (based on multiple comparisons).

From: Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis

Lipid subclass

Total identifiedlipids (n)

Significantlipids (n)a

Sig./total(%)b

Leukocyte-poor RA-SF-OA-SF (n)

/sig. lipid (%)

Leukocyte-rich RA-SFLeukocyte-poor RA-SF (n)

/sig. lipid (%)

Leukocyte-rich RA-SF-OA-SF (n)

/sig. lipid (%)

CAR

14

4

28.6

-

-

4

100.0

4

100.0

Cer

4

4

100.0

-

-

3

75.0

4

100.0

SM

15

12

80.0

-

-

12

100.0

12

100.0

LPC

19

17

89.5

4

23.5

16

94.1

17

100.0

EtherLPC

8

6

75.0

1

16.7

6

100.0

6

100.0

LPE

1

1

100.0

-

-

1

100.0

1

100.0

EtherLPE

1

1

100.0

-

-

1

100.0

1

100.0

PC

41

25

61.0

-

-

20

80.0

25

100.0

EtherPC

22

21

95.5

2

9.5

20

95.2

21

100.0

PE

4

3

75.0

2

66.7

1

33.3

3

100.0

EtherPE

8

5

62.5

-

-

3

60.0

5

100.0

DG

1

1

100.0

1

100.0

-

-

1

-

TG

67

44

65.7

4

9.1

37

84.1

43

97.7

Total

205

144

 

14

 

124

 

143

 
  1. The number and percentage of significant lipids/total identified lipids belonging to each subclass are shown.
  2. CAR acyl carnitine, Cer ceramide, DG diacylglycerol, EtherLPC ether-linked LPC, EtherLPE ether-linked LPE, EtherPC ether-linked PC, EtherPE ether-linked PE, LPC lysophosphatidylcholine, LPE lysophosphatidylethanolamine, PC phosphatidylcholine, SM sphingomyelin, TG triacylglycerol.
  3. aDifferentially expressed lipids were identified by one-way ANOVA and Tukey’s HSD test.
  4. bThe percentage of significant lipids (sig.) divided by the total number of identified lipids.