Table 2 Baseline characteristics of the serum donors.

From: Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis

 

Preclinical RA (n = 18)

Active RA (n = 42)

RA in SR (n = 19)

OA (n = 49)

P value

Female, n (%)

15 (83.3%)

37 (88.1%)

16 (84.2%)

43 (87.8%)

0.941

Age (years)

52.1 ± 9.8

56.6 ± 12.7

55.5 ± 9.2

54.7 ± 11.2

0.836

BMI, kg/m2

23.2 ± 2.4

22.7 ± 2.8

22.1 ± 2.4

23.1 ± 3.3

0.945

RA duration, yr

-

8.9 ± 8.7

9.0 ± 9.9

-

0.955

RF-positive, n (%)

15/18 (83.3)

37/42 (88.1)

13/19 (68.4)

-

0.164

ACPA-positive, n (%)

14/18 (77.8)

31/35 (88.6)

11/16 (68.8)

-

0.118

Laboratory Findings

     

ESR, mm/h

12.2 ± 13.1

28.4 ± 19.2

8.0 ± 6.9

7.6 ± 5.6

<0.001

CRP, mg/dl

0.2 ± 0.3

1.1 ± 1.1

0.2 ± 0.2

0.2 ± 0.5

0.004

Albumin, g/L

4.4 ± 0.2

4.1 ± 0.4

4.2 ± 0.2

4.4 ± 0.2

0.633

Hemoglobin, g/L

14.4 ± 6.2

12.5 ± 1.1

12.9 ± 1.2

13.5 ± 1.2

0.846

DAS28

-

4.7 ± 1.0

1.7 ± 0.7

-

<0.001

MTX, n (%)

-

26 (61.9%)

15 (78.9%)

-

0.309

HCQ, n (%)

-

14 (33.3%)

10 (52.6%)

-

0.104

SSZ, n (%)

-

5 (11.9%)

3 (15.8%)

-

0.705

LEF, n (%)

-

14 (33.3%)

10 (52.6%)

-

0.208

Biologics, n (%)

-

7 (16.7%)

6 (31.6%)

-

0.318

  1. ACPA anti-citrullinated peptide antibody, BMI body mass index, CRP C-reactive protein, ESR erythrocyte sedimentation rate, DAS28 disease activity score in 28 joints, HCQ hydroxychloroquine, MTX methotrexate, LEF leflunomide, RF rheumatoid factor, SR sustained remission, SSZ sulfasalazine.