Fig. 4: Effect of PDE on miR-98-3p expression in bone tissue and oocytes of female rats. | Experimental & Molecular Medicine

Fig. 4: Effect of PDE on miR-98-3p expression in bone tissue and oocytes of female rats.

From: The miR-98-3p/JAG1/Notch1 axis mediates the multigenerational inheritance of osteopenia caused by maternal dexamethasone exposure in female rat offspring

Fig. 4

a RT-qPCR was used to validate candidate miRNAs during the intrauterine period (n = 8). b Expression level of miR-98-3p in long bone tissues of the F1-F3 adult rats (n = 8). c Correlation analysis between the relative expression of miR-98-3p and BV/TV, Tb.N, Tb.Th, and Tb.Sp in F1-F3-generation long bone. d, e Expression changes of miR-98-3p in F1 and F2-generation oocytes (n = 6). GD Gestational day; PW Postnatal week; PDE Prenatal dexamethasone exposure; BV/TV Bone volume/trabecula volume; Tb.N Trabecula number; Tb.Th Trabecula thickness; Tb.Sp Trabecular separation. Mean ± S.E.M., *P < 0.05, **P < 0.01 vs. the control.

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