Fig. 3: Posttranslational regulation of ankyrin-G and structure-dependent ankyrin-G binding partners. | Experimental & Molecular Medicine

Fig. 3: Posttranslational regulation of ankyrin-G and structure-dependent ankyrin-G binding partners.

From: Roles and mechanisms of ankyrin-G in neuropsychiatric disorders

Fig. 3

Ankyrin-G forms four distinct domains: an ankyrin-repeat domain (ANKRD), a spectrin-binding domain, a regulatory domain that includes a death domain (DD), and a C-terminal domain (CTD). Each domain interacts with distinct ion channels, transporters, cell adhesion proteins and signaling molecules, and cytoskeletal elements. *: PSD proteins.

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