Table 1 Phosphorylation motifs of proteins interacting with ankyrin-G.
From: Roles and mechanisms of ankyrin-G in neuropsychiatric disorders
Gene symbols | Protein ID | Protein function | Interaction motif | Phosphorylation sites | Regulatory signaling molecules | Affinity | Related-psychiatric disorder |
|---|---|---|---|---|---|---|---|
CHL1 | O00533 | Cell adhesion | 1174–1185 | Y1185 | −  | ↓ | − |
L1CAM | P32004 | Cell adhesion | 1218–1229 | Y1229 | EphB1/2/3 | ↓ | − |
NFASC | O94856 | Cell adhesion | 1308–1319 | Y1319 | FGF2, NGF | ↓  | − |
NRCAM | Q92823 | Cell adhesion | 1265–1276 | Y1276 | −  | ↓ | ASD |
RHBG | NP_065140.3 | Membrane transporter | 419–421 | Y429 | Src and Syk kinases | ↓ | − |
SCN1B | Q07699 | Ion channel | 183–200 | Y200 | FGF2, FYN | ↓  | − |
SCN1A | P35498 | Ion channel | 1112–1138 | S1122; S1134; S1136 | CK2A1 | ↑  | ASD |
SCN2A | Q99250 | Ion channel | 1102–1128 | S1112; S1124; S1126 | CK2A1 | ↑  | ASD, BD |
SCN3A | Q9NY46 | Ion channel | 1100–1126 | S1110; S1122; S1124 | CK2A1 | ↑  | − |
SCN8A | Q9UQD0 | Ion channel | 1093–1119 | S1103; S1115; S1117 | CK2A1 | ↑  | ASD |
SCHIP-1 | P0DPB3 | Protein binding | 307–352 | N/I | CK2 | ↑  | − |
IQCJ-SCHIP-1 | B3KU38 | Protein binding | 383–428 | N/I | CK2 | ↑  | − |
DAGLA | Q9Y4D2 | Enzymatic activity | 709–847 | S737 | PKA | ↑  | ASD |
USP9X | Q93008 | Enzymatic activity | 1719–1842 | S1593; S1609 | TGFβ, Insulin | ↑ | ASD |
