Fig. 4: CIA mice show MAO-B-dependent cognitive impairment. | Experimental & Molecular Medicine

Fig. 4: CIA mice show MAO-B-dependent cognitive impairment.

From: Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis

Fig. 4

a, d Schematic protocols of the NOR test and NPR test. All objects were positioned in the middle of the first, second, and fourth quadrants of the cage. b, c The summary results of the NOR test of control, CIA and CIA + KDS2010 (10 mg/kg/day) mice (N = 14, 18, and 16; one-way ANOVA, Tukey’s multiple comparisons test). e, f The summary results of the NPR test of control, CIA and CIA + KDS2010 (10 mg/kg/day) mice (N = 9, 10, and 8; one-way ANOVA, Tukey’s multiple comparisons test). Error bars in the graphs indicate the SEM. *P < 0.05; **P < 0.01; ***P < 0.001; ns nonsignificant. Statistical details are provided in Supplementary Table 1.

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