Fig. 2: Serum microbiome compositional profiles between clinical groups.

Composition of the most abundant taxa of the serum EV microbiome in healthy control, COPD, and lung cancer clinical groups at the a phylum and b genus levels was expressed as bar plots based on the relative abundance of taxa within each sample. Composition of the taxa accumulated into their respective coded taxonomies (process detailed in Methods section) was visualized by a c bar plot and d heatmap showing the relative abundance of the accumulated taxa in each clinical sample with the horizontal axis representing each clinical group and the vertical axis grouping the root phyla of the accumulated taxa.