Table 3 Other inhibitors.

From: Dissecting exosome inhibitors: therapeutic insights into small-molecule chemicals against cancer

Name

Chemical Structure

Molecular Weight

Molecular Target

Biological Effects

Lansoprazole

369.36

V-H+-ATPase

- Proton pump inhibitor (PPI)

- Inhibition of acidification

- Inhibition of exosome release

Omeprazole

345.41

V-H+-ATPase

- Proton pump inhibitor (PPI)

- Inhibition of acidification

- Inhibition of exosome release

Esomeprazole

713.12

V-H+-ATPase

- Proton pump inhibitor (PPI)

- Inhibition of acidification

- Inhibition of exosome release

Pantoprazole

383.37

V-H+-ATPase

- Proton pump inhibitor (PPI)

- Inhibition of acidification

- Inhibition of exosome release

Dynasore

322.3

Dynamin

- Clathrin-dependent endocytosis inhibitors

- Noncompetitive inhibitor of dynamin 1 and 2

Methyl-beta-cyclodextrin (MbCD)

1310

Caveolin

- Caveolin-mediated endocytosis inhibitors

  1. The biological characteristics and structures of exosome inhibitors that are involved in decreasing exosome release via other mechanisms.