Fig. 5: The effects of AEC-EVs containing miRNAs in monocytes. | Experimental & Molecular Medicine

Fig. 5: The effects of AEC-EVs containing miRNAs in monocytes.

From: Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells

Fig. 5

a Image of AEC-EVs. b Expression of EV markers. c Protein patterns in EVs. d Effect of AEC-EVs on monocyte activation in the presence of LPS. e Relative expression of miRNAs in EVs. f Levels of IL-1β released from monocytes of asthmatic patients. Data are represented as the means ± SDs, n = 5. The P value was obtained by Student’s t-test, compared to the Lipofectamine-treated group. g Expression of NLRP3 in monocytes. AEC-EV airway epithelial cell-derived extracellular vesicle, ALIX ALG-2-interacting protein X, PBS phosphate-buffered saline, TSG101 tumor susceptibility 101.

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