Fig. 6: Association between miRNAs in plasma and inflammatory status in asthmatic patients. | Experimental & Molecular Medicine

Fig. 6: Association between miRNAs in plasma and inflammatory status in asthmatic patients.

From: Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells

Fig. 6

a Expression of miRNAs in the plasma of asthmatic patients compared to HCs. b Levels of IL-22 in plasma in comparison between patients with EA and those with NA. Data are represented as the means ± SDs. P values were obtained by Student’s t-test. c Correlation between miRNA expression and IL-22 levels. Data are presented as the Pearson correlation coefficient r (P value). d Gating strategy of ILC isolation. e Expression of GATA-3, ROR-γt, and IL-22 in ILCs. f IL-22 levels released from ILCs treated with or without MlEVs in the presence of monocytes. Data are represented as the means ± SDs. P values were obtained by Student’s t test. g Schematic of MlEVs inhibiting airway inflammation. ILC innate lymphoid cell, GATA3 GATA-binding protein 3, Mo monocyte.

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