Fig. 2: The colonization intensity of A. muciniphila affects the gut microecology of mice. | Experimental & Molecular Medicine

Fig. 2: The colonization intensity of A. muciniphila affects the gut microecology of mice.

From: Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases

Fig. 2

A–D Alpha diversity of fecal microflora was measured: (A) ACE diversity index, (B) Chao1 diversity index, (C) Simpson diversity index and (D) Shannon diversity index. The numbers in the histograms represent the abundance of microbial species in each individual. E–G Beta diversity of fecal microflora: (E) Weighted-Tukey HSD diversity index, (F) Weighted-Wilcox diversity index and (G) Weighted UniFrac index. H Venn diagram of the number of bacterial species, and the numbers represent the abundance of microbial species of all individuals in each group. I NMDS analysis was performed to assess the alteration of gut bacterial taxonomic profiles in the three groups. J The difference heatmap of gut bacterial composition at the phylum level. Notes for the numbers are shown in Supplementary Table 3. K The relative abundance of the top 10 most varied bacterial strains at the species level (no others, outliers removed). L, M Statistical results of the relative abundance of Lactobacillus murinus (L) and Lactobacillus reuteri (M) in the mouse feces in the three groups. L, M Significance was determined using Student’s t test; *P < 0.05, **P < 0.01. Data are the mean ± SD.

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