Fig. 2: A theoretical example of sequential mutation events of the first three cell divisions.
From: Grave-to-cradle: human embryonic lineage tracing from the postmortem body
When the zygote divides into two progenies, each progeny having a single different mutation, A and B, these mutations of lineages 1 (L1) and 2 (L2) can be distinguished. After two more divisions, each cell has different combinations of sequential mutation histories. Based on shared and private individual mutations, the phylogenetic tree of each cell can be reconstructed.
