Fig. 7: Inhibition of tumor metastasis by SCCNV injection in murine models.
From: Senescent cancer cell-derived nanovesicle as a personalized therapeutic cancer vaccine
a Timeline for metastasis modeling of 4T1-Luc tumors with vaccination.b Representative bioluminescence images and c luminescence flux showing tumor metastasis to the lungs in 4T1-Luc tumor cell-inoculated mice at various time points. n = 5–6. d Images of lungs harvested on Day 15 and stained with India ink. Tumor nodules were stained white, and normal lung tissues were stained black. Statistical significance was calculated by two-way ANOVA with Holm‒Sidak posttests. *P < 0.05 versus PBS; †P < 0.05 versus CCNVs; ‡P < 0.05 versus SCCNVs; ‖P < 0.05 versus aPD-L1.
