Table 1 Improved cardiac function and morphology in CAR KO hearts 30 days post-MI.
From: CAR links hypoxia signaling to improved survival after myocardial infarction
WT sham (n = 12) | KO sham (n = 7) | WT MI (n = 11) | KO MI (n = 9) | |
|---|---|---|---|---|
BW [g] | 28.88 ± 1.00 | 28.50 ± 1.25 | 29.58 ± 0.96 | 29.82 ± 0.79 |
HW [mg] | 162.30 ± 8.07 | 118.87 ± 15.55 | 198.34 ± 12.82* | 143.18 ± 10.52 |
HW/BW [mg/g] | 5.62 ± 0.20 | 4.14 ± 0.43* | 6.70 ± 0.35* | 4.84 ± 0.39 |
LVD diastole [mm] | 4.66 ± 0.11 | 3.96 ± 0.21** | 5.26 ± 0.14** | 4.53 ± 0.11 |
LVD systole [mm] | 3.51 ± 0.08 | 2.98 ± 0.19* | 4.34 ± 0.13**** | 3.57 ± 0.09 |
FS [%] | 24.72 ± 0.73 | 24.88 ± 1.98 | 17.64 ± 0.86**** | 21.01 ± 1.04 |
EF [%] | 48.81 ± 1.35 | 49.86 ± 3.49 | 36.95 ± 1.75*** | 42.59 ± 1.94 |
SV [μl] | 35.01 ± 2.33 | 24.24 ± 2.18 | 39.56 ± 3.78 | 26.13 ± 2.41 |
HR [bpm] | 438.33 ± 14.18 | 506.14 ± 10.30** | 496.64 ± 11.94* | 520.44 ± 18.36*** |
CO [ml/min] | 15.17 ± 0.86 | 12.35 ± 1.31 | 19.55 ± 1.92 | 13.73 ± 1.54 |
