Fig. 3: Relapse mutation signature (RMS) derived using LASSO regression and chromatin remodeling signature in the study population. | Experimental & Molecular Medicine

Fig. 3: Relapse mutation signature (RMS) derived using LASSO regression and chromatin remodeling signature in the study population.

From: The role of the genomic mutation signature and tumor mutation burden on relapse risk prediction in head and neck squamous cell carcinoma after concurrent chemoradiotherapy

Fig. 3: Relapse mutation signature (RMS) derived using LASSO regression and chromatin remodeling signature in the study population.

a Bar plot shows the mutation rate of 30 relapse-associated candidate genes and (b) 14 chromatin remodeling-associated candidate genes. c LASSO coefficient profiles of mutated genes and (d) coefficient profile plot used to determine the optimal lambda for LASSO regression according to 30 relapse-associated candidate genes.

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