Fig. 3: Different mutational spectra between shared and private mutations. | Experimental & Molecular Medicine

Fig. 3: Different mutational spectra between shared and private mutations.

From: Metastatic pattern of ovarian cancer delineated by tracing the evolution of mitochondrial DNA mutations

Fig. 3: Different mutational spectra between shared and private mutations.The alt text for this image may have been generated using AI.

a Number of shared mutations (blue), primary private mutations (PP, purple), and metastatic private mutations (MP, pink) in each patient. b Heteroplasmy levels among the three groups. Bar represents median values. c Base substitution spectrum among the three groups. Mutations are denoted based on pyrimidine base. H, H-strand; L, L-strand. d Mutation proportions in mtDNA D-loop and coding regions among the three groups. e Mutation density in mtDNA D-loop and coding regions among the three groups.

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