Fig. 4: Histone modifications in cancer. | Experimental & Molecular Medicine

Fig. 4: Histone modifications in cancer.

From: Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

Fig. 4: Histone modifications in cancer.The alternative text for this image may have been generated using AI.

Histone tails can be posttranslationally modified by various molecules in the presence of enzymes. Examples include histone methylation, acetylation, phosphorylation, glycosylation, guanylation, succinate, SUMO, and ubiquitination. These histone posttranslational modifications are involved in protein expression and degradation, changes in enzymatic activity, signaling, energy production, the immune response, and various other cancer cell activities.

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