Table 2 Enrichment analysis based on OMIM disease libraries for H2O2-decreased DEGs restored by NAM.
Term | Overlap | Adjusted P value | Combined Score | Genes |
|---|---|---|---|---|
Osteoporosis | 2/11 | 0.017127866 | 251.2087451 | COL1A2;VDR |
Hypothyroidism | 1/11 | 0.136997884 | 49.20758107 | TG |
Ehlers-Danlos | 1/11 | 0.136997884 | 49.20758107 | COL1A2 |
Anomalies | 1/13 | 0.136997884 | 38.63591875 | RUNX2 |
Myopia | 1/15 | 0.136997884 | 31.38589486 | COL2A1 |
Hypogonadism | 1/15 | 0.136997884 | 31.38589486 | CHD7 |
Lymphoma | 1/22 | 0.165094954 | 17.87363593 | BCL7A |
Deafness | 2/111 | 0.165094954 | 6.558998122 | TMIE;COL2A1 |
Obesity | 1/31 | 0.1805597 | 10.64289988 | SDC3 |
Neuropathy | 1/35 | 0.181466527 | 8.818608039 | SLC12A6 |
