Fig. 2: Schematic summarizing the indirect regulation of AMPK in the liver by miRs via the regulation of activators and repressors of AMPK. | Experimental & Molecular Medicine

Fig. 2: Schematic summarizing the indirect regulation of AMPK in the liver by miRs via the regulation of activators and repressors of AMPK.

From: MicroRNA regulation of AMPK in nonalcoholic fatty liver disease

Fig. 2

LKB1 and CaMKK2 are known upstream kinases of AMPK, activating AMPK via Thr-172 phosphorylation (p) in the α subunit. Red arrows indicate activation, and black blunt arrows indicate inhibition.

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