Table 3 Text mining score and overall association score of neurological diseases associated with CHI3L1, APP, and DRD2 on the Open Targets Platform.

From: Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

CHI3L1-neurological diseases			APP-neurological diseases				DRD2-neurological diseases
Name	Text Mining	Overall Association Score	Name	Text Mining	Overall Association Score	Name		Text Mining	Overall Association Score
Alzheimer disease	0.919	0.113	Alzheimer disease	0.995	0.824		Schizophrenia	0.942	0.732
Obstructive sleep apnea	0.793	0.096	Neuroblastoma	0.931	0.113		Parkinson disease	0.826	0.636
Amyotrophic lateral sclerosis	0.667	0.081	Dravet syndrome	0.898	0.109		Alcohol dependence	0.779	0.611
Pick disease	0.663	0.081	Parkinson disease	0.774	0.094		Psychosis	0.757	0.624
Age-related macular degeneration	0.625	0.076	Experimental autoimmune encephalomyelitis	0.694	0.084		Alzheimer disease	0.668	0.428
Carotid atherosclerosis	0.525	0.064	Schizophrenia	0.693	0.092		Insomnia	0.648	0.097
Glioblastoma multiforme	0.493	0.069	Autism	0.690	0.083		Autism	0.631	0.624
Temporal arteritis	0.464	0.056	Cerebral amyloid angiopathy	0.689	0.361		Prolactin-producing pituitary gland adenoma	0.613	0.083
Astrocytoma	0.438	0.055	Brain ischemia	0.607	0.073		Glioblastoma	0.608	0.073
Glioblastoma	0.435	0.053	Glioblastoma	0.513	0.062		Attention deficit hyperactivity disorder	0.572	0.658
Sporadic amyotrophic lateral sclerosis	0.425	0.052	Familial Alzheimer disease	0.455	0.055		Experimental autoimmune encephalomyelitis	0.488	0.059
Lewy body dementia	0.365	0.044	Huntington disease	0.419	0.051		Lewy body dementia	0.425	0.051
Polymyositis	0.312	0.038	Nervous system disease	0.331	0.040		Conduct disorder	0.419	0.556
Cerebral amyloid angiopathy	0.305	0.037	Stroke	0.317	0.392		Huntington disease	0.417	0.393
Dermatomyositis	0.277	0.034	Age-related macular degeneration	0.291	0.035		Post-traumatic stress disorder	0.384	0.585
Glioma	0.238	0.029	Amyotrophic lateral sclerosis	0.289	0.050		Catalepsy	0.377	0.045
Schizophrenia	0.237	0.377	Fragile X syndrome	0.268	0.032		Dyslexia	0.364	0.044
Multiple sclerosis	0.221	0.027	Neurodegenerative disease	0.264	0.032		Cocaine dependence	0.330	0.469
Cognitive disorder	0.218	0.027	Tauopathy	0.228	0.027		Fabry disease	0.305	0.0371
Relapsing-remitting multiple sclerosis	0.213	0.026	Brain injury	0.226	0.027		Migraine disorder	0.282	0.590

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Table 3 Text mining score and overall association score of neurological diseases associated with CHI3L1, APP, and DRD2 on the Open Targets Platform.

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