Table 4 Text mining score and overall association score of cardiovascular diseases associated with CHI3L1, VCAM1, and ITGAX on the Open Targets Platform.

From: Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer

CHI3L1-cardiovascular diseases			VCAM1-cardiovascular diseases			ITGAX-cardiovascular diseases
Name	Text Mining	Overall Association Score	Name	Text Mining	Overall Association Score	Name	Text Mining	Overall Association Score
Hypertension	0.854	0.104	Atherosclerosis	0.876	0.106	Atherosclerosis	0.798	0.097
Coronary artery disease	0.842	0.102	Cardiovascular disease	0.851	0.104	Behcet’s syndrome	0.236	0.029
Peripheral arterial disease	0.750	0.091	Endothelial dysfunction	0.799	0.097	Hypertension	0.149	0.030
Cardiovascular disease	0.707	0.086	Hypertension	0.706	0.086	Coronary artery disease	0.148	0.018
Atrial fibrillation	0.678	0.082	Dilated cardiomyopathy	0.627	0.076	Atrial fibrillation	0.146	0.018
Acute coronary syndrome	0.627	0.076	Duchenne muscular dystrophy	0.602	0.075	Mucocutaneous lymph node syndrome	0.122	0.015
Coronary stenosis	0.626	0.076	Arteriosclerosis	0.538	0.065	Atrial heart septal defect	0.076	0.009
Portal hypertension	0.608	0.074	Stroke	0.533	0.065	Vasculitis	0.065	0.008
Carotid atherosclerosis	0.525	0.064	Coronary artery disease	0.512	0.062	Myocarditis	0.064	0.008
Myocardial Ischemia	0.522	0.063	Vasculitis	0.341	0.042	Carotid atherosclerosis	0.061	0.007
Atherosclerosis	0.511	0.062	Heart failure	0.321	0.039	Abdominal Aortic Aneurysm	0.061	0.007
Temporal arteritis	0.464	0.056	Mucocutaneous lymph node syndrome	0.292	0.035	Congestive heart failure	0.061	0.007
Endothelial dysfunction	0.456	0.055	Systemic scleroderma	0.289	0.035	Arteritis	0.055	0.007
Cerebral amyloid angiopathy	0.305	0.037	Acute coronary syndrome	0.245	0.030	Cardiovascular disease	0.053	0.024
Systemic scleroderma	0.276	0.034	Rheumatic heart disease	0.230	0.028	Systemic scleroderma	0.041	0.005
Acute myocardial infarction	0.249	0.030	Atrial fibrillation	0.229	0.028	Thromboangiitis obliterans	0.036	0.004
Congestive heart failure	0.193	0.023	Pulmonary arterial hypertension	0.212	0.026	Aortic aneurysm	0.035	0.004
Idiopathic pulmonary arterial hypertension	0.188	0.023	Myocardial Ischemia	0.211	0.026	Acute myocardial infarction	0.031	0.004
Diabetic macular edema	0.182	0.022	Acute myocardial infarction	0.197	0.024	Thrombotic disease	0.030	0.004
Vascular dementia	0.155	0.019	Myocardial infarction	0.193	0.023	Coronary atherosclerosis	0.030	0.004

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Table 4 Text mining score and overall association score of cardiovascular diseases associated with CHI3L1, VCAM1, and ITGAX on the Open Targets Platform.

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