Fig. 4: Population of IL-10-producing PD-L1^highSca-1⁺ ILCs in contact hypersensitivity.

a, b Representative flow cytometry images (a) and histograms (b) of PD-L1^highSca-1⁺ ILC subsets in the spleen, cLN, and ears of mice with or without CHS (n = 12). c, d Representative flow cytometry images (c) and histograms (d) showing the frequency and number of IL-10⁺ ILCs in PD-L1^highSca-1⁺ ILC subsets from the spleen, cLN, and ear tissues (n = 12). The data are presented as representative images (a, c) of the mean ± SEM (b, d) from four independent experiments (n = 3 per group for each experiment). *p < 0.05 and **p < 0.01 versus the ACE group according to Student’s t test. e, f Representative images (e) and histograms (f) of the frequencies of PD-L1^highSca-1⁺ ILC subsets among IL⁻10⁺ ILCs from the spleen, cLN, and ear in mice (n = 6) from two independent experiments (n = 3 per group for each experiment). *p < 0.05 and **p < 0.01 versus the ACE group according to Student’s t test.