Fig. 4: Cytokine and chemokine analysis following SARS-CoV-2 infection in the lungs of the double-transgenic (double-Tg) mice.
a Cytokine and chemokine protein levels in the lungs of the double-Tg mice were measured using multiplex immune analysis at 0 (mock), 3, and 6 days post-infection. Symbols represent means ± SEM. Statistically significant differences between the groups were determined using unpaired two-tailed t-tests. b Heat map of cytokine and chemokine analysis results as measured with multiplex immune analysis. The fold change was calculated by comparing expression levels of the double-Tg mice with those of the mock group and log2[fold change] shown in the heat map.
