Table 1 Overview of all iPSC-derived motor neuron protocols used in IPN.
From: Advances and challenges in modeling inherited peripheral neuropathies using iPSCs
Reference | SMAD inhibition | Patterning | Inclusion of DAPT |
|---|---|---|---|
Hu et al., 158 | - | RA, SHH | - |
Reinhardt et al., 159 | SB, DM, CHIR | RA, PMA | - |
Saporta et al. 15 | SB, DM | RA, SAG | - |
LDN, SB, CHIR | RA, SAG | Yes | |
Amoroso et al., 160 | LDN, SB | RA, PMA | - |
Faye et al. 22 | SD, DM, Noggin, FGF2 | RA, SHH | - |
Fernandopulle et al., 161 | Induced expression of the transcription factors NGN2, ISL1, and LHX3 (‘NIL’) | ||
