Table 3 Summary of the effects of PARP1 on the recruitment of RECQL4 and BLM at DSB sites.
Cell line or treatment | Recruitment at DSB site | |
|---|---|---|
RECQL4 | BLM | |
PARP1 KO cell line | No recruitment compared with WT cells | Delayed recruitment relative to WT cells |
+ PARP1 inhibitor (olaparib) | No recruitment compared with WT cells | Delayed recruitment relative to WT cells |
