Fig. 4: HAV in vivo infection models currently available to assess innate immunity. | Experimental & Molecular Medicine

Fig. 4: HAV in vivo infection models currently available to assess innate immunity.

From: Redefining the immune landscape of hepatitis A virus infection

Fig. 4

A schematic of different animals that are supportive of HAV infection, showing the advantages and disadvantages of their utilization. a Primates and pigs. b Mammals prone to infection with HAV-like viral strains. c Wild-type (WT) mice with KO of MAVS or IFNAR1. d Albumin-urokinase-type plasminogen activator/severe combined immunodeficient (Alb/uPASCID) mice with humanized livers.

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