Fig. 6: Knockout (GAS5 or SMARCA4) and overexpression (miR-423-3p) similarly repress oncogenic potential ability for both in vivo Ras-Tg spontaneous liver cancer and xenograft mouse models. | Experimental & Molecular Medicine

Fig. 6: Knockout (GAS5 or SMARCA4) and overexpression (miR-423-3p) similarly repress oncogenic potential ability for both in vivo Ras-Tg spontaneous liver cancer and xenograft mouse models.

From: Oncogenic function of growth arrest-specific transcript 5 by competing with miR-423-3p to regulate SMARCA4 in hepatocellular carcinoma

Fig. 6

a The representative ultrasonography images of Ras-Tg mice injected with si-Cont, si-Gas5, mmu-miR-423-3p and si-Smarca4 and liver image at 24 weeks of age. b The Smarca4 expression was performed using western blotting analysis with liver tissues from the Ras-Tg mouse model. c Five mice in each group were subcutaneously injected with Hepa1-6 cells transfected with si-Cont or siRNA specific for the indicated gene and mmu-miR-423-3p mimic. Then, they were observed with mouse images, fluorescence and mass image.

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