Fig. 8: A schematic diagram illustrates how the targeted delivery of circp53 via EVs suppresses cancer progression by opening the mPTP. | Experimental & Molecular Medicine

Fig. 8: A schematic diagram illustrates how the targeted delivery of circp53 via EVs suppresses cancer progression by opening the mPTP.

From: Extracellular vesicle-mediated delivery of circp53 suppresses the progression of multiple cancers by activating the CypD/TRAP/HSP90 pathway

Fig. 8: A schematic diagram illustrates how the targeted delivery of circp53 via EVs suppresses cancer progression by opening the mPTP.

a, The process of packaging tumor-targeted EVs that overexpress circp53. b, The mechanism of tumor cell cytotoxicity mediated by EVs that overexpress circp53. c, The targeted delivery of circp53-enriched EVs to CRC and MM.

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