Table 3 Risk assessment of MCI in a simple and multivariable logistic regression model in T2DM.

From: Cholesterol-driven pathological astrocytic responses in diabetes-associated cognitive impairment through astrocytic SCAP accumulation and NF-κB–C3 signaling modulation

 

Univariate analysis

Multivariate analysis

P value

OR (95% CI)

P value

OR (95% CI)

Age (years)

<0.001*

1.048

1.122

0.003#

1.021

1.102

Gender (female/male)

0.026*

1.080

3.437

0.791

0.555

2.164

Education (years)

<0.001*

0.754

0.911

0.005#

0.763

0.954

BMI (kg/m2)

0.033*

0.847

0.993

0.111

0.862

1.015

Diabetes duration (years)

0.616

0.969

1.055

Hypertension duration (years)

0.576

0.977

1.043

HbA1c (%)

0.534

0.891

1.250

FBG (mmol/l)

0.068

0.809

1.008

2h-PBG (mmol/l)

0.323

0.968

1.105

TG (mmol/l)

0.520

0.755

1.153

Total cholesterol (mmol/l)

0.452

0.848

1.447

LDL-C (mmol/l)

0.768

0.660

1.359

HDL-C (mmol/l)

0.265

0.689

3.864

C3 (μg/mL)

0.024*

1.000

1.003

0.028#

1.000

1.003

  1. *P < 0.05 (simple logistic regression was used).
  2. #P < 0.05 (multivariable logistic regression was used).