Table 1 Characteristics of the MRC National Survey of Health and Development (sample restricted to those with complete data on BMI and inflammatory markers at age 60–64 and perceived physical fatigability at age 68 (maximum n = 1580))
From: Are BMI and inflammatory markers independently associated with physical fatigability in old age?
Men | Women | |||
|---|---|---|---|---|
n a | % or Mean (SD) | n a | % or Mean (SD) | |
Physical Fatigability Scale Score at age 68 | 760 | 13.2 (8.9) | 820 | 16.0 (9.1) |
BMI at age 60–64b | ||||
Underweight | 10 | 1.3 | 25 | 3.1 |
Normal weight | 193 | 25.4 | 271 | 33.1 |
Overweight | 367 | 48.3 | 305 | 37.2 |
Obese | 190 | 25.0 | 219 | 26.7 |
CRP (mg/l) at age 60–64 | ||||
<1.00 | 197 | 25.9 | 181 | 22.1 |
1.00–3.00 | 339 | 44.6 | 371 | 45.2 |
3.01–10.00 | 185 | 24.3 | 224 | 27.3 |
>10.00 | 39 | 5.1 | 44 | 5.4 |
IL-6 (pg/mL) at age 60–64 | ||||
<1.50 | 281 | 37.0 | 319 | 38.9 |
1.50–2.50 | 225 | 29.6 | 251 | 30.6 |
2.51–8.49 | 216 | 28.4 | 216 | 26.3 |
≥8.50 | 38 | 5.0 | 34 | 4.2 |
Covariates (at age 60–64 unless indicated otherwise) | ||||
Leisure time physical activity | ||||
Inactive | 452 | 60.9 | 474 | 59.1 |
Moderately active | 107 | 14.4 | 125 | 15.6 |
Most active | 183 | 24.7 | 203 | 25.3 |
Smoking status | ||||
Current | 67 | 9.5 | 77 | 9.9 |
Ex | 435 | 61.5 | 427 | 55.0 |
Never | 205 | 29.0 | 272 | 35.1 |
Symptoms of anxiety & depression | ||||
Yes | 87 | 11.7 | 165 | 20.6 |
No | 660 | 88.4 | 636 | 79.4 |
Type II diabetes | ||||
Yes | 60 | 7.9 | 34 | 4.2 |
No | 700 | 92.1 | 785 | 95.9 |
Cardiovascular disease | ||||
Yes | 61 | 8.9 | 25 | 3.3 |
No | 621 | 91.1 | 725 | 96.7 |
Respiratory symptoms | ||||
Yes | 120 | 17.6 | 134 | 17.7 |
No | 561 | 82.4 | 624 | 82.3 |
Medication usec | ||||
Yes | 327 | 43.0d | 360 | 43.9d |
No | 433 | 57.0 | 460 | 56.1 |
Educational level attained by age 26 | ||||
None | 194 | 27.1 | 197 | 25.1 |
CSE, clerical course or equivalent | 35 | 4.9 | 73 | 9.3 |
O levels, or their equivalents | 111 | 15.5 | 225 | 28.7 |
A levels, or their equivalents | 236 | 32.9 | 237 | 30.2 |
Degree or higher | 141 | 19.7 | 52 | 6.6 |
Occupational class at age 53 | ||||
Low (IV or V) | 64 | 8.5 | 113 | 13.8 |
Middle (IIINM or IIIM) | 233 | 30.9 | 358 | 43.7 |
High (I or II) | 458 | 60.7 | 348 | 42.5 |
Fatigue at age 43 | 443 | 61.0 | 284 | 36.1 |
No | 443 | 61.0 | 284 | 36.1 |
Occasional | 229 | 31.5 | 356 | 45.3 |
Frequent | 54 | 7.4 | 146 | 18.6 |
