Table 1 Demographic characteristics of study participants

From: Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and metabolic syndrome in healthy subjects and schizophrenia patients

Variables

SCH patients with MetS (n = 70)

Normal weight SCH patients (n = 190)

P level

MetS patients (n = 155)

Healthy controls (n = 100)

P level

Age (years)

46.54 ± 13.08

43.8 ± 9.12

0.097

43.24 ± 8.44

41.23 ± 7.71

0.057

Female/male ratio

51 (72.86%)/19 (27.14%)

68 (35.79%)/122 (64.21%)

<0.001*

95 (61.29%)/60 (38.71%)

52 (52%)/48 (48%)

0.1427

BMI (kg/m2)

34.06 ± 4.13

21.56 ± 2.09

<0.001

40.87 ± 7.55

22.42 ± 2.15

<0.001

Waist circumference (cm)

103.31 ± 13.19

77.90 ± 6.71

<0.001

113.34 ± 15.52

76.38 ± 9.18

<0.001

Hip circumference (cm)

104 ± 20.58

95.17 ± 9.95

0.288

123.17 ± 14.88

95.5 ± 6.97

<0.001

Waist-to-hip ratio

0.98 ± 0.15

0.82 ± 0.04

0.008

0.93 ± 0.12

0.8 ± 0.07

<0.001

Systolic blood pressure (mm Hg)

136.10 ± 20.84

118.02 ± 16.03

<0.001

143.94 ± 24.55

112.67 ± 9.62

<0.001

Diastolic blood pressure (mm Hg)

86.76 ± 12.87

74.44 ± 13

<0.001

87.64 ± 14.76

71.5 ± 4.74

<0.001

Current cigarette smokers (n, %)

41 (58.57%)

94 (49.47%)

0.193

43 (27.74%)

23 (23%)

0.399

Fasting glucose (mmol/l)

5.55 ± 0.7

5.14 ± 0.65

0.093

6.66 ± 2.12

5.12 ± 0.35

<0.001

Total cholesterol (mmol/l)

5.67 ± 1.02

5.09 ± 1

0.115

4.41 ± 1.04

4.71 ± 0.43

0.139

HDL-cholesterol (mmol/l)

1.01 ± 0.27

1.2 ± 0.43

0.183

1.17 ± 0.29

1.49 ± 0.38

<0.001

LDL-cholesterol (mmol/l)

3.83 ± 0.82

3.34 ± 0.9

0.133

2.66 ± 0.86

2.7 ± 0.38

0.784

Triglycerides (mmol/l)

1.5 ± 0.5

1.15 ± 0.53

0.066

1.41 ± 0.77

0.86 ± 0.35

<0.001

Nitrites (µmol/l)

31.37 ± 18.31

11.82 ± 7.23

0.004

4.36 ± 1.8

4.09 ± 1.32

0.551

  1. Data are expressed as mean  ±  s.d.
  2. SCH schizophrenia, MetS metabolic syndrome, BMI body mass index, HDL high-density lipoprotein, LDL low-density lipoprotein
  3. *P value calculated using Pearson’s Chi-square test