Table 4 Associations between peripheral blood SLC6A4 CpG5 methylation levels and measures of fat mass in children age 17 years from the RAINE cohort
From: Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood
Phenotype | Standardised CpG5 |
|---|---|
BMI at 17 years; standardised; adjusted for sex, age | |
n | 843 |
β | −0.167 |
p-value | <0.001** |
95% CI | (−0.246, −0.088) |
Waist circumference at 17 years; standardised; adjusted for sex, age | |
n | 813 |
β | −0.102 |
p-value | 0.011* |
95% CI | (−0.182, −0.0234) |
Subcutaneous fat at 17 years; standardised; adjusted for sex, age | |
n | 774 |
β | −0.136 |
p-value | <0.001*** |
95% CI | (−0.216, −0.057) |
Visceral fat; standardised; adjusted for sex, age | |
n | 648 |
β | 0.025 |
p-value | 0.557 |
95% CI | (−0.059, 0.111) |
Subscapular skinfolds at 17 years; standarised; adjusted for sex, age | |
n | 785 |
β | −0.123 |
p-value | 0.002** |
95% CI | (−0.201, −0.045) |
Abdominal skinfold at 17; standardised; adjusted for sex, age | |
n | 776 |
β | −0.099 |
p-value | 0.008** |
95% CI | (−0.174, −0.025) |
Suprailiac skinfold at 17; standardised; adjusted for sex, age | |
n | 777 |
β | −0.1096 |
p-value | 0.004** |
95% CI | (−0.185, −0.034) |
