Fig. 2
From: Long-acting CCK analogue NN9056 lowers food intake and body weight in obese Göttingen Minipigs
Mean daily food intake (a), body weight (BW) development (b), accumulated food intake from days 1 to 77 (c) and BW change from days 1 to 77 in obese Göttingen Minipigs dosed subcutaneously (s.c.) with either vehicle (black ■, n = 8), NN9056 low-dose group (light grey ▲, n = 7) or NN9056 high-dose group (dark grey ▼, n = 7). Data are presented as mean ± SEM. BW change and accumulated food intake was compared by one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparisons test. **p < 0.01, ***p < 0.001. Grey shading: Periods with anaesthesia/fasting due to dual-energy x-ray absorptiometry (DEXA) scanning or metabolic tests. Dose change 1: dose change from 5 to 3 nmol/kg in the low-dose group. Dose change 2: dose change from 3 to 2 nmol/kg in the low-dose group
