Fig. 5: Oral glucose tolerance tests in male PAT-ectomized and sham control mice on chow diet and after 8- and 16-week HFD-feeding.

Circulating glucose levels at indicated time points and AUC in response to oral glucose load in PAT-ectomized and sham controls mice on a chow diet (CD; n = 7–9 mice/group), after b 8 weeks on HFD (n = 8–10 mice/group), and c 16 weeks on HFD (n = 8–10 mice/group). Circulating insulin levels at indicated time points and AUC in response to oral glucose load in PAT-ectomized and sham controls mice on d chow diet, after e 8 weeks on HFD, and f 16 weeks on HFD. All values are expressed as mean ± SEM. *p < 0.05.