Table 1 Patient characteristics at the time of ICU admission.
Non-obese (BMI < 30, n = 49) | Obese (BMI ≥ 30, n = 18) | p value | |
|---|---|---|---|
Characteristics | |||
Body Mass Index, kg/m2 | 26.0 [24.4–27.7] | 32.6 [31.2–34.5] | <0.0001 |
Age, years | 65 [59–72] | 66.5 [57–72] | 0.99 |
Male | 38 (76%) | 12 (24%) | 0.36 |
Female | 11 (65%) | 6 (35%) | 0.36 |
APACHE II | 14 (12–19) | 17 (9–23) | 0.54 |
SOFA | 7 [5–8.5] | 4 (4–9) | 0.72 |
Time from first COVID signs to ICU admission, days | 12 [8–15.75] | 10 [7–13.5] | 0.35 |
Medical history | |||
Cardio vascular disease | 11 (22%) | 7 (39%) | 0.18 |
Hypertension | 23 (47%) | 8 (44%) | 0.53 |
Chronic kidney disease | 0 (0%) | 1 (6%) | 0.10 |
Chronic obstructive pulmonary disease | 3 (6%) | 3 (17%) | 0.18 |
Diabetes mellitus | 11 (22%) | 4 (22%) | 0.98 |
Hematological malignancy | 1 (2%) | 0 (0%) | 0.54 |
Metastatic neoplasm | 4 (8%) | 1 (6%) | 0.72 |
Clinical and laboratory parameters | |||
Mean arterial pressure, mmHg | 90 [85–94] | 84 [78–94] | 0.07 |
Heart rate, beats/min | 86 [77–98] | 88 [81–94] | 0.98 |
Temperature, °Celsius | 38.7 [38.0 −39.5] | 38.1 [36.9–38.9] | 0.02 |
Respiratory rate, beats/min | 22 (20–25) | 22 (20–26) | 0.87 |
PEEP, cmH2O | 12 (10–14) | 12 (12–14) | 0.15 |
Tidal volumeIBW, ml/kg | 6.4 [6.0–6.8] | 6.4 [5.9–8.2] | 0.78 |
PaO2/FiO2 ratio, mmHg | 144 [95–180] | 144 [107–180] | 0.60 |
Creatinine, μmol/L | 79 [65–101] | 97 [58–229] | 0.28 |
Bilirubin | 7.0 (6–12) | 6.0 (4–12) | 0.71 |
Alanine aminotransferase, U/L | 38.0 [21.0–56.0] | 44.0 [23.5–94.0] | 0.38 |
Aspartate aminotransferase, U/L | 52.0 [37.0–67.0] | 55.0 [31.5–63.5] | 0.36 |
Leukocyte count, ×109/L | 8.2 [6.2–10.8] | 8.8 [0.7–10.0] | 0.63 |
CRP, mg/L | 218 [169–291] | 245 [136–327] | 0.43 |
Procalcitonin, μg/L | 0.76 [0.39–1.99] | 0.53 [0.28–1.56] | 0.52 |
Ferritin, μg/L | 1486 [720–2265] | 1129 [724–2404] | 0.74 |
D-dimer, ng/mL | 3330 [1830–10370] | 2560 [1545–2560] | 0.48 |
