Fig. 5: Sex-linked chromosomes contribute to the sexual dimorphism in offspring adipose transcriptome. | International Journal of Obesity

Fig. 5: Sex-linked chromosomes contribute to the sexual dimorphism in offspring adipose transcriptome.

From: Maternal high-fat diet programs white and brown adipose tissue lipidome and transcriptome in offspring in a sex- and tissue-dependent manner in mice

Fig. 5

Volcano plots of the DEG between females and males in a moC and b moHF in VAT; in c moC and in d moHF in SAT and in e moC and in f moHF in BAT with selected genes linked to the X and Y chromosomes involved in metabolism and embryonic development. Genes residing on the X-chromosome are marked in red and those on the Y-chromosome are marked in light blue. The pink background indicates upregulation in females and the blue background indicates upregulation in males. Gray dots indicate significantly deregulated genes (FDR < 0.1) and black dots indicate non-significant genes. Genes that are highly significant with foldchange outside the range of the graph are placed in boxes on the side in the graph. F-moC, n = 5, M-moC, n = 5, F-moHF, n = 6 and M-moHF, n = 3.

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