Table 1 Descriptive characteristics of the study population.

From: Cord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight

 

Study population postnatal (12 months) rapid growth analyses N = 375

Study population childhood overweight analyses N = 249

Normal growth N = 268 (71.47%)

Rapid growth N = 107 (28.53%)

P value

Normal weight N = 193 (77.51%)

Overweight N = 56 (22.49%)

P value

Cohort membership

  

<0.01

  

<0.01

ENVIRONAGE

73 (27.24%)

31 (28.97%)

 

-

-

 

INMA

62 (23.13%)

24 (22.43%)

 

58 (30.05%)

25 (44.64%)

 

Piccolipiù

81 (30.22%)

16 (14.95%)

 

74 (38.34%)

4 (7.14%)

 

Rhea

52 (19.40%)

36 (33.64%)

 

61 (31.61%)

27 (48.21%)

 

Sex, boy

146 (54.48%)

45 (42.06%)

0.04

97 (50.26%)

30 (53.57%)

0.78

Child ethnicity, maternal origin different from study country

22 (8.21%)

11 (10.28%)

0.66

12 (6.22%)

2 (3.57%)

0.67

Delivery, caesarean

66 (24.72)

33 (30.84)

0.28

67 (34.90)

24 (42.86)

0.35

Gestation age, weeks

39.54 (±1.36)

38.36 (±1.72)

<0.01

39.33 (±1.51)

38.88 (±1.61)

0.05

Gestation age, <37 weeks

9 (3.36%)

16 (14.95%)

<0.01

9 (4.66%)

5 (8.93%)

0.37

Parity, primiparous

119 (44.40%)

58 (54.21%)

0.11

76 (39.38%)

28 (50.00%)

0.21

Maternal age, years

31.34 (±4.43)

30.28 (±4.68)

0.04

32.17 (±4.62)

30.50 (±4.95)

0.02

Maternal age, <32 years

151 (56.34%)

69 (64.49%)

0.18

89 (46.11%)

38 (67.86%)

<0.01

Maternal education level,

  

0.07

  

0.36

(i) Low (no diploma or primary school diploma)

28 (10.45%)

14 (13.08%)

 

21 (10.88%)

8 (14.29%)

 

(ii) Medium (secondary school diploma)

105 (39.18%)

53 (49.53%)

 

90 (46.63%)

30 (53.57%)

 

(iii) High (university degree or higher education qualification)

135 (50.37%)

40 (37.38%)

 

82 (42.49%)

18 (32.14%)

 

Pre-pregnancy maternal BMI, Kilogram/ metre2

23.64 (±4.43)

24.27 (±4.74)

0.22

23.14 (±4.35)

25.73 (±4.72)

<0.01

Prepregnancy maternal BMI, Overweight or obese (BMI ≥ 25)

77 (28.73%)

35 (32.71%)

0.52

52 (26.94%)

25 (44.64%)

0.02

Maternal weight gain over the pregnancy, Kilograms

13.52 (5.03)

13.63 (5.55)

0.85

12.96 (4.79)

14.20 (5.95)

0.11

Maternal weight gain over the pregnancy, excess

83 (30.97%)

38 (35.51%)

0.47

49 (25.39%)

27 (48.21%)

<0.01

Maternal pregnancy tobacco smoke, yes

42 (15.67%)

23 (21.50%)

0.23

35 (18.13%)

14 (25.00%)

0.34

Obesogenic factors score, numeric (range 0-7)

2.10 (±1.30)

2.61 (±1.30)

<0.01

1.95 (±1.27)

2.86 (±1.37)

<0.01

Postnatal rapid growth at 12 months, yes

0 (0.00%)

107 (100.00%)

<0.01

40 (20.73%)

30 (53.57%)

<0.01

Child overweight (WHO cut-off), yes

26 (14.21%)

30 (41.67%)

<0.01

0 (0.00%)

56 (100.00%)

<0.01

Child overweight (IOTF cut-offs), yes

29 (15.85%)

33 (45.83%)

<0.01

11 (5.70%)

49 (87.50%)

<0.01

Child age at the BMI measurement, years

5.33 (1.00)

5.48 (1.03)

0.30

5.25 (1.00)

5.93 (0.82)

<0.01

  1. Number (%) and mean (±standard deviation) are reported for categorical and continuous variables, respectively. P values from chi-square and t-test statistics are reported for categorical and continuous variables, respectively, and are bolded if <0.05.