Table 1 Descriptive statistics of study participants. Quantitative traits are reported as median [1st–3rd quartiles].

From: ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19

 

TwinsUK

METSIM

FUSION

N [% female]

765 [100]

426 [0]

280 [47]

Age (years)

59 [52–65]

54 [51–59]

60 [55–65]

BMI (kg/m2)

25.6 [23.3–28.8]

26.2 [24.6–28.6]

26.7 [24.2–28.8]

Serum fasting insulin (pmol/L)

38.0 [25.0–59.5]

35.4 [25.2–55.8]

43.8 [28.8–59.1]

Fasting plasma glucose (mmol/L)

4.9 [4.6–5.2]

5.7 [5.4–6.0]

5.9 [5.6–6.3]

Serum HDL (mmol/L)

1.80 [1.53–2.14]

1.45 [1.20–1.70]

1.44 [1.20–1.70]

Serum LDL (mmol/L)

3.18 [2.57–3.82]

3.43 [2.96–3.96]

3.34 [2.78–3.89]

Serum triglycerides (mmol/l)

0.96 [0.72–1.33]

1.17 [0.88–1.62]

1.17 [0.89–1.56]

Systolic BP (mmHg)

128 [118–139]

132 [123–141]

133 [121–145]

Diastolic BP (mmHg)

78 [71–85]

87 [81–93]

82 [76–87]

Adipose tissue ACE2 expression (TMM-adjusted CPMs)

1.86 [1.16–3.05]

1.25 [0.82–1.83]

1.15 [1.07–2.62]

  1. Statistics for all traits are calculated including only participants without diabetes. ACE2 expression levels are reported as trimmed mean of M-values (TMM)-adjusted counts per million (CPMs).
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