Table 2 Associations of cardiorespiratory fitness and objectively measured physical activity and sedentary time with Adipo-IR and MRI-derived fat depots.

From: Associations of objectively measured physical activity, sedentary time and cardiorespiratory fitness with adipose tissue insulin resistance and ectopic fat

 

CRF (mL∙kg−1∙min−1)bc

Sedentary time (per 30 mins)ac

MVPA (per 30 mins)ab

 

β (95% CI)

P-value

β (95% CI)

P-value

β (95% CI)

P-value

Model 1

Adipo-IR (AU)

−0.33 (−0.50 to −0.16)

<0.001

0.68 (0.18 to 1.18)

0.007

−1.08 (−2.14 to −0.01)

0.049

Liver fat (%)

−0.07 (−0.11 to −0.04)

<0.001

0.04 (−0.07 to 0.16)

0.472

−0.15 (−0.40 to 0.09)

0.217

VAT (L)

−0.06 (−0.08 to −0.04)

<0.001

0.01 (−0.04 to 0.07)

0.605

−0.05 (−0.19 to 0.08)

0.442

ScAT (L)

−0.19 (−0.24 to −0.14)

<0.001

0.07 (−0.12 to 0.25)

0.483

−0.38 (−0.73 to −0.03)

0.034

Model 2

Adipo-IR (AU)

−0.15 (−0.35 to 0.06)

0.154

0.68 (0.27 to 1.10)

<0.001

−1.13 (−2.04 to −0.21)

0.016

Liver fat (%)

−0.00 (−0.05 to 0.04)

0.873

0.06 (−0.05 to 0.18)

0.282

−0.21 (−0.43 to 0.01)

0.062

VAT (L)

−0.02 (−0.04 to −0.01)

0.001

0.05 (0.01 to 0.08)

0.005

−0.09 (−0.17 to 0.00)

0.054

ScAT (L)

−0.10 (−0.13 to −0.07)

<0.001

0.05 (−0.05 to 0.15)

0.311

0.12 (−0.16 to 0.40)

0.416

Model 3

Adipo-IR (AU)

−0.02 (−0.23 to 0.19)

0.822

0.59 (0.01 to 1.08)

0.019

−0.65 (−1.71 to 0.41)

0.227

Liver fat (%)

−0.01 (−0.05 to 0.04)

0.827

0.01 (−0.12 to 0.15)

0.827

−0.20 (−0.47 to 0.08)

0.156

VAT (L)

−0.02 (−0.04 to −0.01)

0.003

0.04 (0.00 to 0.08)

0.048

−0.04 (−0.14 to 0.07)

0.501

ScAT (L)

−0.10 (−0.13 to −0.06)

<0.001

−0.01 (−0.10 to 0.08)

0.774

0.13 (−0.14 to 0.39)

0.344

  1. Model 1 adjusted for study, sex, ethnicity, age and device wear time. Model 2 adjusted for all of the previous covariates plus BMI, glucose, TAG and HDL. Model 3 adjusted for all of the previous covariates plus aCRF, bsedentary time or cMVPA. Bold font indicates that associations remained statistically significant after applying Holm-Bonferroni sequential correction for multiple comparisons.
  2. Adipo-IR adipose tissue insulin resistance index, BMI body mass index, CRF cardiorespiratory fitness, HDL high-density lipoprotein, MVPA moderate-to-vigorous physical activity, ScAT subcutaneous abdominal adipose tissue, TAG triacylglycerol, VAT visceral adipose tissue.
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