Table 1 Participants’ characteristics.
Primary WL failure (LowEBMIL) | Successful WL (HighEBMIL) | P-value | |
|---|---|---|---|
N | 20 women | 20 women | na |
Age at study (years) | 50 [47;57] | 50 [44;58] | na |
Time from surgery (years) | 5 [3;6] | 5 [4;6] | na |
Preoperative BMI (kg/m2) | 42.4 [40.2;45.8] | 42.2 [40.8;45.4] | na |
Max postoperative EBMIL recorded (%) | 34% [27;41] | 80% [76;85] | <0.001 |
BMI at study (kg/m2) | 39.4 [37.5;42.0] | 29.4 [28.2;31.1] | <0.001 |
EBMIL at study (%) | 23% [9;27] | 74% [70;83] | <0.001 |
Body weight at study (kg) | 109.9 [99.7;115.4] | 78.9 [74.7;84.3] | <0.001 |
Weight loss at study (kg, % of total body weight) | 9.5 kg [4.5;13], 8.6% [3.8;11] | 36 kg [32;44], 32% [28;36] | <0.001, <0.001 |
Fat mass at study (kg, % of body weight) | 48 kg [44;55], 46% [44;49] | 29 kg [28;32], 38% [36;41] | <0.001, <0.001 |
Lean mass at study (kg) | 55 [52;60] | 44 [42;49] | <0.001 |
Polygenic score for BMI | 38.86 [38.79;38.94] | 38.92 [38.81;39.04] | 0.358 |
Hba1c at study (mmol/mol) | 37 [36;40] | 35 [33;37] | 0.003 |
HOMA2-IR at study fasting | 1.5 [1.2;2.2] | 1.0 [0.8;1.2] | <0.001 |
P-leptin (ng/mL) fasting | 79 [56;106] | 34 [28;40] | <0.001 |
P-leptin receptor (ng/mL) fasting | 23 [19;28] | 25 [21;34] | 0.436 |
Basal energy expenditure (kcal/day) resting | 1551 [1481;1672] | 1414 [1284;1478] | 0.006 |
Steps per day | 3204 [2800;6540] | 4619 [3607;5763] | 0.437 |
Self-reported at home energy intake (kcal/day) | 1705 [1307;2038] | 1655 [1311;2151] | 0.696 |
Self reported energy % from carbohydrates | 45 [42;47] | 43 [37;49] | 0.869 |
Self reported energy % from protein | 19 [16;22] | 20 [16;24] | 0.887 |
Self reported energy % from fat | 36 [31;38] | 36 [31;42] | 0.981 |
