Fig. 1: Flow of participants.

NNS non-nutritive sweetened. Some data have been reproduced with permission from Harrold JA, Hill S, Radu C, Thomas P, Thorp P, Hardman CA, et al. Effects of non-nutritive sweetened beverages versus water after a 12-week weight loss programme: a randomised controlled trial. Obesity (Silver Spring). 2023;31(8):1996–2008. © 2023 The Authors. aWeek 12 data were missing for 11 participants (n = 6 for water; n = 5 for NNS beverages) who remained in the trial. bWeek 52 data were missing for four participants (n = 2 for water; n = 2 for NNS beverages) who remained in the trial. These individuals were, therefore, not included in the analyses using the complete cases data set for the week-52 timepoint but were included in the analyses using the multiple imputation and last observation carried forward data sets. They may also contribute to analyses at future timepoints.