Fig. 6: miR-548ag promotes DPP4 expression in L02 through activation of TLR(7/8)/NF-κB pathway.
From: miR-548ag promotes DPP4 expression in hepatocytes through activation of TLR(7/8)/NF-κB pathway
mRNA expression levels of (A) miR-548ag, (B) TLR7/8, DPP4 in L02 cells after transfection with miR-548ag; C Protein expression levels of TLR(7/8), key proteins of NF-κB pathway, DPP4 in L02 cells after transfection with miR-548ag (D) L02 glucose consumption levels; E mRNA expression levels of TLR7/8, DPP4 in L02 cells after transfection with miR-548ag inhibitor; F Protein expression levels of TLR(7/8), key proteins of NF-κB pathway, DPP4 in L02 cells after transfection with miR-548ag inhibitor; G L02 glucose consumption levels; H Protein expression levels of TLR(7/8), key proteins of NF-κB pathway, DPP4 in L02 cells after transfection with TLR7 interference fragment; I Cell glucose consumption of L02; J The protein expression levels of L02 cells were transfected with TLR7 interference fragments after miR-548ag was modulated; K Glucose consumption of L02; L Protein expression level of L02 cells after transfection with TLR8 interference fragment; M Cell glucose consumption of L02; N Protein expression levels of L02 cells after transfection of TLR8 interference fragments with up-regulated miR-548ag; O Glucose consumption of L02 (Rank sum test, *P < 0.05, **P < 0.01, ***P < 0.001, the difference was statistically significant).
