Table 2 Peripheral blood T cell Leptin (LepR/CD295) and Insulin (InsR/CD220) receptor expression before and after 3 days of 50% calorie restriction.

From: Calorie restriction-induced leptin reduction and T-lymphocyte activation in blood and adipose tissue in men with overweight and obesity

 

CD295 (LepR) MFI

 

CD220 (InsR) MFI

 

Cell Type

Pre

Post

p

Pre

Post

p

CD4+ CD25+

230 ± 24

234 ± 27

0.627

86 ± 9

98 ± 17

0.009

CD4+ CD69+

6949 ± 8826

4589 ± 4677

0.425

1292 ± 1151

1323 ± 1226

0.954

CD8+ CD25+

269 ± 17

303 ± 75

0.155

123 ± 15

141 ± 27

0.061

CD8+ CD69+

1213 ± 211

1262 ± 392

0.635

566 ± 77

580 ± 72

0.644

  1. Mean ± SD values shown and differences between the two days analysed by two-tailed, paired, Student’s t tests or non-parametric equivalent where data were non-normally distribution (Shapiro–Wilk’s p > 0.05). n = 12 for all, p-values shown.
  2. InsR Insulin Receptor, LepR Leptin Receptor, MFI median fluorescence intensity.
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