Table 5 Changes in BMI measurements and laboratory results in children treated with anti-obesity medications (AOMs)- all AOMs and by medication type.

BMI-Z Score

Males

3.15 (0.05) ^a

2.63 (0.04) ^b

2.93 (0.04) ^c

2.87 (0.06) ^c

<0.001

<0.001

0.987

Females

2.98 (0.05) ^a

2.47 (0.03) ^b

2.76 (0.03) ^c

2.73 (0.04) ^c

<0.001

Males

140.8 (3.3) ^a

96.4 (2.8) ^b

126.4 (4.2) ^c

115.8 (3.5) ^d

<0.001

<0.001

0.384

Females

128.6 (2.6) ^a

92.2 (1.8) ^b

115.6 (2.8) ^c

109.2 (2.3) ^c

<0.001

Males

6.8 (0.10) ^a

5.8 (0.08) ^b

6.3 (0.08) ^c

6.5 (0.16) ^a,c

<0.001

<0.001

0.266

Females

6.4 (0.07) ^a

5.6 (0.05) ^b

5.9 (0.05) ^c

6.0 (0.10) ^c

<0.001

Males

153.7 (5.7) ^a

99.9 (4.4) ^b

141.7 (8.1) ^a

141.8 (8.0) ^a

<0.001

0.745

0.511

Females

152.5 (4.2) ^a

106.9 (3.2) ^b

135.6 (5.8) ^c

135.7 (5.9) ^c

<0.001

Males

42.0 (0.6) ^a

48.0 (0.5) ^b

42.2 (0.7) ^a,c

43.8 (0.5) ^c

<0.001

0.686

0.227

Females

42.1 (0.5) ^a

47.0 (0.4) ^b

43.2 (0.5) ^a,c

44.2 (0.4) ^c

<0.001

Males

96.3 (1.4)

92.1 (2.0)

95.3 (1.6)

93.3 (2.0)

0.298

0.659

0.758

Females

97.9 (1.3)

93.3 (1.6)

93.9 (1.5)

94.2 (1.6)

0.065

Males

167.6 (1.9) ^a

150.8 (1.5) ^b

164.3 (2.1) ^a

165.9 (2.6) ^a

<0.001

0.321

0.996

Females

168.6 (1.4) ^a

152.5 (1.1) ^b

165.4 (1.6) ^a

167.3 (2.0) ^a

<0.001

Males

33.0 (1.4)

30.0 (1.8)

29.5 (1.5)

29.7 (1.9)

0.286

0.012

0.996

Females

36.0 (1.2)

33.1 (1.5)

31.9 (1.4)

32.3 (1.6)

0.087

Males

2.98 (0.07) ^a

2.46 (0.05) ^b

2.81 (0.05) ^c

2.68 (0.07) ^c

<0.001

0.002

0.965

Females

2.83 (0.06) ^a

2.34 (0.04) ^b

2.68 (0.04) ^c

2.59 (0.05) ^c

<0.001

Males

153.4 (4.1) ^a

101.0 (3.6) ^b

135.2 (5.0) ^c

126.1 (4.5) ^c

<0.001

<0.001

0.322

Females

136.4 (2.7) ^a

95.1 (2.3) ^b

121.7 (3.3) ^c

115.6 (2.8) ^c

<0.001

Males

6.7 (0.13) ^a

5.8 (0.10) ^b

6.3 (0.10) ^c

6.5 (0.20) ^ac

<0.001

<0.001

0.385

Females

6.5 (0.08) ^a

5.6 (0.06) ^b

5.9 (0.06) ^c

5.9 (0.11) ^c

<0.001

Males

159.6 (7.6) ^a

101.6 (5.8) ^b

144.1 (11.0) ^a

144.4 (11.2) ^a

<0.001

0.413

0.614

Females

156.3 (5.2) ^a

106.8 (4.0) ^b

134.2 (7.1) ^c

134.7 (7.3) ^c

<0.001

Males

41.5 (0.7) ^a

47.0 (0.5) ^b

42.2 (0.8) ^a

43.0 (0.6) ^a

<0.001

0.125

0.438

Females

42.1 (0.5) ^a

46.7 (0.4) ^b

43.4 (0.6) ^a,c

44.1 (0.5) ^c

<0.001

Males

94.9 (1.7)

92.8 (2.6)

94.5 (1.9)

93.9 (2.6)

0.920

0.539

0.735

Females

98.2 (1.5)

93.1 (1.9)

94.3 (1.7)

94.1 (1.9)

0.114

Males

166.4 (2.4) ^a

150.7 (1.8) ^b

164.0 (3.5) ^a

164.3 (3.5) ^a

<0.001

0.178

0.987

Females

169.0 (1.6) ^a

152.1 (1.2) ^b

165.6 (1.9) ^a

166.9 (2.2) ^a

<0.001

Males

32.2 (1.6)

30.1 (2.2)

27.9 (1.8)

29.4 (2.2)

0.336

0.008

0.999

Females

35.9 (1.4)

33.3 (1.7)

31.4 (1.6)

33.1 (1.9)

0.190

Males

3.45 (0.05) ^a

3.08 (0.05) ^b

3.22 (0.05) ^c

3.31 (0.06) ^ac

<0.001

<0.001

0.978

Females

3.28 (0.05) ^a

2.95 (0.05) ^b

3.06 (0.05) ^c

3.16 (0.06) ^ac

<0.001

Males

92.8 (1.3) ^a

82.4 (1.0) ^b

86.8 (1.7) ^c

87.4 (1.2) ^c

<0.001

0.876

0.972

Females

93.1 (1.3) ^a

82.2 (1.2) ^b

86.4 (2.1) ^b,c

88.4 (1.5) ^c

<0.001

Males

6.9 (0.17) ^a

5.7 (0.14) ^b

6.2 (0.14) ^c

6.5 (0.24) ^a,c

<0.001

0.010

0.254

Females

6.3 (0.14) ^a

5.6 (0.11) ^b

5.9 (0.10) ^c

6.4 (0.21) ^a

<0.001

Males

136.0 (7.6) ^a

95.8 (6.1) ^b

135.2 (10.0) ^a

135.3 (10.1) ^a

<0.001

0.123

0.983

Females

144.0 (6.3) ^a

107.8 (4.9) ^b

142.2 (9.0) ^a

142.9 (9.1) ^a

<0.001

Males

42.8 (1.2) ^a

50.4 (0.9) ^b

42.4 (1.4) ^a

45.5 (1.0) ^a

<0.001

0.181

0.768

Females

41.8 (1.1) ^a

48.2 (0.8) ^b

42.4 (1.2) ^a

44.5 (1.0) ^a

<0.001

Males

99.6 (2.3)

92.1 (3.1)

98.4 (2.8)

93.3 (3.1)

0.154

0.861

0.464

Females

97.1 (2.7)

95.5 (3.6)

93.2 (3.2)

96.0 (3.6)

0.818

Males

170.1 (2.9) ^a

151.5 (2.3) ^b

166.5 (3.5) ^a

168.3 (3.8) ^a

<0.001

0.812

0.803

Females

167.8 (3.1) ^a

154.3 (2.4) ^b

165.9 (3.6) ^a

170.6 (4.5) ^a

<0.001

Males

35.2 (2.8)

30.0 (3.5)

33.9 (3.2)

30.1 (3.5)

0.549

0.684

0.952

Females

37.3 (2.5)

32.0 (3.2)

33.0 (2.9)

30.5 (3.5)

0.355

Males

3.37 (0.57)

2.63 (0.45)

3.24 (0.45)

2.31 (0.52)

0.452

0.023

0.402

Females

2.42 (0.37)

1.93 (0.21)

2.32 (0.21)

2.48 (0.26)

0.323

Males

88.0 (4.4)

82.0 (3.1)

91.0 (5.0)

90.9 (3.3)

0.232

0.249

0.848

Females

85.2 (3.7)

81.1 (2.5)

82.7 (4.5)

89.3 (2.8)

0.187

Males

7.7 (1.1)

5.6 (0.9)

5.9 (0.9)

7.5 (1.6)

0.424

0.043

0.354

Females

6.1 (0.4)

5.6 (0.4)

5.6 (0.3)

5.3 (0.6)

0.692

Males

163.8 (41.2)

99.6 (38.1)

162.7 (50.0)

162.8 (50.4)

0.612

0.014

0.402

Females

107.2 (15.4)

99.9 (12.2)

85.0 (21.2)

85.5 (21.8)

0.780

Males

46.5 (5.2)

47.0 (4.8)

32.5 (9.1)

43.3 (6.4)

0.547

0.411

0.657

Females

45.1 (3.1)

47.6 (2.5)

44.0 (4.0)

43.5 (3.1)

0.740

Males

98.8 (13.8)

81.4 (15.1)

68.5 (23.9)

81.4 (15.1)

0.669

0.886

0.839

Females

100.2 (7.7)

74.8 (10.4)

85.6 (9.4)

74.8 (10.4)

0.164

Males

171.4 (17.2)

145.0 (16.0)

118.0 (29.9)

174.7 (21.1)

0.336

0.721

0.338

Females

161.0 (8.2)

143.3 (6.6)

147.5 (10.3)

142.8 (12.2)

0.380

Males

26.3 (7.6)

28.8 (8.3)

20.5 (13.1)

30.3 (9.3)

0.934

0.530

0.740

Females

29.2 (6.7)

37.1 (9.1)

36.3 (8.1)

21.6 (10.8)

0.643