Fig. 7: Endothelial cells in the human stomach express FGF23.
From: High fat diet induces gastric production of fibroblast growth factor 23 (FGF23)
A–C Blood vessels in the stomach of a normal-weight subject showing endothelial cells faintly immunoreactive for FGF23 (A) but strongly for PECAM (B). D Gastric blood vessels with interconnections at the base of gastric glands in patients with obesity. E–G Gastric endothelial cells of a patient with obesity display strong immunoreactivity for FGF23 (E) and PECAM (F). (Normal-weight: n = 6; patients with obesity: n = 6). A dotted line marks interconnected blood vessels. Sections were counterstained with DAPI. Scale bars: 20 μm (A-C, E-G), 50 μm (D). FGF23 fibroblast growth factor 23, PECAM platelet endothelial cell adhesion molecule.
