Table 1 Baseline characteristics of participants.
From: Predictors of BMI reduction with phentermine/topiramate in adolescents with obesity
Placebo | Mid-dose PHEN/TPM | Top-dose PHEN/TPM | |
|---|---|---|---|
N | 56 | 54 | 112 |
Age, years (Mean ± SD) | 14.0 (1.4) | 14.1 (1.3) | 14.0 (1.3) |
Age category, N (%)a | |||
12–14 years | 34 (60.7) | 33 (61.1) | 68 (60.7) |
15–16 years | 22 (39.3) | 21 (38.9) | 44 (39.3) |
Sex, N (%) | |||
Female | 30 (53.6) | 28 (51.9) | 63 (56.2) |
Male | 26 (46.4) | 26 (48.1) | 49 (43.8) |
Race, N (%) | |||
American Indian or Alaska Native | 0 (0.0) | 0 (0.0) | 1 (0.9) |
Asian | 0 (0.0) | 0 (0.0) | 1 (0.9) |
Black or African American | 10 (17.9) | 14 (25.9) | 36 (32.1) |
Otherb | 4 (7.1) | 4 (7.4) | 4 (3.6) |
White | 42 (75.0) | 36 (66.7) | 70 (62.5) |
Ethnicity, N (%) | |||
Hispanic or Latino | 13 (23.6) | 25 (47.2) | 33 (29.5) |
Non-Hispanic or Non-Latino | 42 (76.4) | 28 (52.8) | 79 (70.5) |
Missing | 1 | 1 | 0 |
Race/Ethnicity, N (%) | |||
Hispanic and/or not White | 27 (48.2) | 38 (71.7) | 72 (64.3) |
Non-Hispanic White | 29 (51.8) | 15 (28.3) | 40 (35.7) |
Missing | 0 | 1 | 0 |
Baseline BMI, kg/m2 (Mean ± SD) | 36.4 (6.4) | 36.9 (6.7) | 39.0 (7.5) |
% of the 95th BMI percentile (Mean ± SD) | 136.7 (23.0) | 138.7 (25.2) | 147.0 (28.7) |
Tanner stage, N (%) | |||
Stages 2 and 3 | 23 (41.1) | 16 (29.6) | 37 (33.0) |
Stages 4 and 5 | 33 (58.9) | 38 (70.4) | 75 (67.0) |
Glycemic status, N (%) | |||
Normoglycemic | 40 (75.5) | 37 (69.8) | 82 (77.4) |
Prediabetes | 13 (24.5) | 16 (30.2) | 24 (22.6) |
Missing | 3 | 1 | 6 |
Depression status, N (%) | |||
None | 50 (89.3) | 45 (83.3) | 83 (76.1) |
Mild | 6 (10.7) | 9 (16.7) | 26 (23.9) |
Missing | 0 | 0 | 3 |
CANTAB-Spatial Span Score (Mean ± SD) | 6.6 (1.4) | 6.8 (1.5) | 6.8 (1.4) |
CANTAB-Spatial Span Score, N (%) | |||
Low (<7) | 27 (48.2) | 17 (31.5) | 52 (46.4) |
High (≥7) | 29 (51.8) | 37 (68.5) | 60 (53.6) |
IWQOL-Kids total score (Mean ± SD) [Missing] | 87.6 (10.3) | 85.5 (12.9) | 82.6 (14.3) [2] |
IWQOL-Kids total score, N (%) | |||
Low (<85) | 18 (32.1) | 25 (46.3) | 48 (43.6) |
High (≥85) | 38 (67.9) | 29 (53.7) | 62 (56.4) |
Missing | 0 | 0 | 2 |
