Table 3 Association between BMI trajectory groups and cardiometabolic risk in logistic regression models.

From: Life-long body mass index trajectories and cardiometabolic biomarkers-the Danish diet, cancer, and health-next generations cohort

 

Model 1

Model 2

Model 3

Hypertension

OR

95% CI

OR

95% CI

OR

95% CI

Stable low BMI

Ref.

  

Ref.

  

Ref.

  

Gradual BMI increase

1.72

1.62

1.83

1.43

1.34

1.53

1.40

1.31

1.50

Steeper BMI increase

2.44

2.27

2.62

2.56

2.37

2.76

2.39

2.22

2.58

Early high BMI

2.13

1.82

2.49

3.02

2.57

3.56

2.76

2.34

3.26

Dyslipidemia

        

Stable low BMI

Ref.

  

Ref.

 

Ref.

 

Gradual BMI increase

2.56

2.20

2.96

2.30

1.97

2.68

2.31

1.99

2.70

Steeper BMI increase

6.39

5.51

7.41

6.21

5.33

7.22

6.37

5.47

7.42

Early high BMI

5.51

4.27

7.11

5.86

4.53

7.60

6.04

4.65

7.83

Pre-diabetes and diabetes

       

Stable low BMI

Ref.

  

Ref.

  

Ref.

  

Gradual BMI increase

2.10

1.64

2.69

1.85

1.44

2.39

1.67

1.29

2.16

Steeper BMI increase

7.01

5.53

8.88

8.11

6.36

10.34

6.12

4.76

7.85

Early high BMI

8.34

5.88

11.85

14.97

10.41

21.53

10.37

7.10

15.15

  1. Model 1 was crude model; Model 2 was adjusted for age, sex, and smoking; Model 3 was adjusted for age, sex, smoking, and medication.
  2. Hypertension was defined as systolic/diastolic BP ≥ 140/90 mmHg, self-reported doctor diagnosis of hypertension, or use of BP-lowering medication. Dyslipidemia was defined as having triglycerides >2.0 mmol/l or HDL < 1.0 mmol/l based upon the recommendations by the National Heart Foundation [2] and the Australian Diabetes Society [3]. Glucose metabolism status was determined by the American Diabetes Association criteria based on HbA1c.
  3. Prediabetes status was based in the range of 39-46 mmol/mol and cases of type 2 diabetes were defined as ≥48 mmol/mol [4].
  4. OR odds ratio, CI confidence interval, Ref reference.
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