Table 1 The schedule of behavioral measures in the POWERS study.
Variable(s) of interest | Procedure | Timepoints | |||
|---|---|---|---|---|---|
BL | T0 | T4 | T12 | ||
Energy intake and eating-related behaviors | |||||
Food intake, macronutrient distribution, diet energy density, diet variety | Multiple-item Test Meal | Â | x | x | Â |
Hedonic eating | Eating in the Absence of Hunger laboratory meal and snack | Â | x | x | Â |
Healthiness and tastiness preference and food choice | Food Choice Task | x | x | x | x |
Neural circuits engagement during food choice | Food Choice Task during functional MRI (at CUIMC only) | Â | x | x | Â |
Learning and reward circuit engagement during palatable tastes and their anticipatory cues | Taste and Anticipatory Cue Gustatory Task during functional MRI (at DDPT only) | Â | x | x | Â |
Midbrain dopamine levels | Neuromelanin-sensitive MRI | Â | x | x | Â |
White matter tractography and connectivity | Diffusion-weight MRI | Â | x | x | Â |
Psychological factors related to eating behavior and weight | |||||
Weight-related self-monitoring | Weight Control Strategies Scale - self-monitoring subscale items | Â | x | x | x |
Eating patterns | Action for HEAlth in Diabetes (Look AHEAD) Eating Patterns Questionnaire | x | x | x | x |
Meal replacement use | Meal replacement frequency question | Â | x | x | x |
Binge and loss-of-control eating | Questionnaire on Eating and Weight Patterns-5 | x | x | x | x |
Dietary restraint, disinhibition and hunger | Three Factor Eating Questionnaire-51 item version | x | x | x | x |
Food preferences | Geiselman Food Preference Questionnaire | x | x | x | x |
Stress or emotional eating | Palatable Eating Motives Scale—Coping subscale | x | x | x | x |
Food craving | Food Craving Questionnaire-Trait-Reduced | x | x | x | x |
Hedonic hunger | Power of Food Scale | x | x | x | x |
Weight stigma | Weight Bias Internalized Scale | x | x | Â | Â |
Weight loss goals | Goals and Relative Weight Questionnaire | x | Â | Â | Â |
Confidence in weight loss maintenance | Confidence in Weight Loss Maintenance Questionnaire | Â | x | Â | Â |
Free-living physical activity | |||||
Objective steps, activity counts and time in sedentary behavior and activity by intensity | ActiGraph GT3X+ (wrist-worn actigraphy) | x | x | x | x |
Self-report time in moderate and vigorous activity by domain | Global Physical Activity Questionnaire | x | x | x | x |
Sleep | |||||
Objective sleep duration, efficiency, latency, timing, wake after sleep onset, frequency of awakenings, and ambient light | ActiGraph GT3X+ (wrist-worn actigraphy) | x | x | x | x |
Objective sleep quality and disturbances (e.g., apneas and hypopneas) | zMachine Synergy System (polysomnography) | x | x | x | x |
Self-report sleep quality | Pittsburgh Sleep Quality Index | x | x | x | x |
Self-report chronotype | Morningness-Eveningness Questionnaire | x | x | x | x |