Table 1 Summary of strategies for antimicrobial dental materials
From: Advancing antimicrobial strategies for managing oral biofilm infections
Name | Advantages | Drawbacks |
|---|---|---|
Antimicrobial agent release (locally) | Strong and broad-spectrum antimicrobial activity, high local doses at site of interest, less systemic toxicity, and minimize the risk of antimicrobial resistance | Reservoir exhaustion issue, and short-acting |
Contact-killing | Long-term antimicrobial activity, non-toxic and non-irritant properties | Surface biofouling, bacteriostatic effect (most) |
Multi-functional strategy | Multiple functions (e.g., antibacterial, antifungal, antiviral, remineralizing, protein-repellent properties) | Selection of more combinations for synergistic antimicrobial and beneficial properties |
