Fig. 4 | International Journal of Oral Science

Fig. 4

From: The role of mechanotransduction versus hypoxia during simulated orthodontic compressive strain—an in vitro study of human periodontal ligament fibroblasts

Fig. 4

Effects of mechanotransduction vs. oxygen supply on hPDL fibroblast RANKL/OPG expression. a Gene and b protein expression of OPG in the presence of pressure under normoxic (Lumox®) and hypoxic (polystyrene) conditions (N = 3, n = 9). c Gene expression and the corresponding d protein secretion of (soluble) RANKL by hPDL fibroblasts (N = 2, n = 6). Calculated RANKL/OPG ratio for the e transcriptional and f protein levels. Bars indicate mean values ± standard deviation. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001. AU = arbitrary units

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